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The Journal of Heredity 1979:70(1):27-30
© 1979 The American Genetic Association 70:27-30

research-article

Cataract-webbed Peromyscus

I. Genetics of cataract in P. maniculatus

RUTH S. ANDERSON, research associate, and ROBERT P. BURNS, professor of ophthalmology

Department of Ophthalmology, University of Oregon Health Sciences Center Portland, Oregon 97201

Abstract

Cataract-webbed (cw) in the deer mouse (Peromyscus maniculatus) is a recessive mutant that is manifested by syndactyly (involving soft tissues) and eye defects including cataract. Within cw/cw mice, the age at which cataract first appears is genetically controlled. Evidence for the activity of genetic modifiers is the early appearance of cataracts in the offspring of parents that developed cataracts at early ages.


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