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The Journal of Heredity 1979:70(1):78-80
© 1979 The American Genetic Association 70:78-80

other

Assignment of the H-Y antigen gene to the short arm of chromosome Y

J. M. RARY, professor of gynecology, D. K. CUMMINGS, professor of gynecology, H. W. JONES, JR., and J. A. ROCK

Department of Gynecology and Obstetrics, Eastern Virginia Medical School Norfolk, VA 23501
Johns Hopkins University School of Medicine Baltimore, MD 21205

Abstract

We have presented two cases strongly supporting a Y chromosome short-arm location for the H-Y antigen gene. The first case was H-Y antigen-positive with an isochromosome for the short arm of the Y with no long arm of the Y being present. The other case was H-Y antigen-negative in fibroblasts from an individual with a 46,X,i(Yq) karyotype with no short arm of the Y present. The two cases presented also confirmed previous reports that the testicular forming gene is also located on the short arm of chromosome Y.


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