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The Journal of Heredity 1979:70(1):9-12
© 1979 The American Genetic Association 70:9-12

research-article

Fertile dominant spotting in the house mouse

A new allele at the W locus

J. -L. GUENET, G. MARCHAL, G. MILON, P. TAMBOURIN, and F. WENDLING

The first three authors are affiliated with the Département de Biologie Moléculaire, Institut Pasteur, 25 rue du Dr. Roux, Paris; the last two authors are affiliated with the Institut du RadiumBiologie, Faculté des Sciences, Bâtiment 110, 91405 Orsay, France

Abstract

Recognition of a new allele (Wf) at the W locus of the mouse is based on genetic analysis and demonstration of defective hair pigmentation, macrocytic anemia, and defects in pluripotent hemopoietic stem cells. Unlike other alleles of the W series, this one does not result in sterility.


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