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The Journal of Heredity 1981:72(1):3-5
© 1981 The American Genetic Association 72:3-5

research-article

Age-related pigmentation changes in the coats of allophenic mice

John Gearhart, and Mary Lou Oster-Granite

Department of Anatomy, University of Maryland School of Medicine Baltimore, Maryland 21201

Abstract

Hair pigmentation and patterns of pigmentation change with age in the coats of BALB/cByI {leftrightarrow} C57BL/6J allophenic mice. These changes are particularly evident on the dorsum where there is an increase in the proportion of white areas at the expense of agouti and black areas. The most plausible explanation for these changes is that they represent a continuous selection for one of the two genotypes of cells from which the melanoblasts and hair follicles of these animals are derived.


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