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The Journal of Heredity 1981:72(2):107-112
© 1981 The American Genetic Association 72:107-112


research-article

Inheritance of alternative states of the fused gene in mice

D. K. Belyaev, A. O. Ruvinsky, and P. M. Borodin

Dr. Belyaev is director, and Drs. Ruvinsky and Borodin are scientific workers, Institute of Cytology and Genetics of the Siberian Department of the Academy of Sciences U.S.S.R., Novosibirsk-90, U.S.S.R.

Abstract

The genetics of the fused (Fu) gene in the house mouse, Mus musculus, was studied by use of the closely linked recessive marker, tufted (tf). Evidence was obtained indicating that Fu passes from a phenotypically active state to inactive: Fu {rightleftarrows} [Fu]. These alternative states may be genetically transmitted. It is suggested that the activation of a "dormant" Fu gene may underlie this passage.


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