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The Journal of Heredity 1981:72(2):129-130
© 1981 The American Genetic Association 72:129-130

other

Variation in spermatozoal levels of phosphoglycerate kinase-2 in mice

Robert P. Erickson, and Kenneth Harper

The authors are, respectively, professor and research assistant in the Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109. The research was aided by National Institutes of Health grant HD 11738. They thank Benjamin Taylor of The Jackson Laboratory, Bar Harbor, Maine for mating pairs of the LXB RI lines, and Mrs. Rena Jones for excellent secretarial assistance.

Abstract

Litter size differences exist between inbred strains of mice with high and low spermatozoal phosphoglycerate kinase-2 activity, but an examination of these two variables in recombinant inbred lines between the two strains suggest that the variables are not related. An examination of spermatozoal cAMP concentrations in these recombinant inbred lines demonstrated no correlation with litter size. Furthermore, spermatozoal cAMP concentrations were demonstrated to be under multigenic control.


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