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The Journal of Heredity 1981:72(4):294-296
© 1981 The American Genetic Association 72:294-296

other

Assignment of retinal dystrophy (rdy) to linkage group IV of the rat

Matthew M. LaVail

Department of Anatomy, University of California, School of Medicine San Francisco, CA 94143.

Abstract

The retinal dystrophy gene, rdy, in the rat displays autosomal linkage of 19.0 ± 1.7 percent with nonagouti, a, and 31.8 ± 4.1 percent with Svp-1 in linkage group IV. The data are consistent with the linear order rdy—a—Svp-1, but the orientation of this sequence with respect to the centromere is not known. A congenic strain has been developed from some of the testcross animals in which retinal dystrophic and heterozygous control rats of both pink-eyed and black-eyed phenotypes can be distinguished with pigmentation marker genes.


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