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The Journal of Heredity 1983:74(4):273-276
© 1983 The American Genetic Association 74:273-276

research-article

Hereditary progressive retinal atrophy in the Abyssinian cat

Kristina Narfstrom

the Department of Surgery, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences and at the Department of Ophthalmology, University Hospital, Linköping University Sweden

Please address reprint request to Dr. Narfstrom, Department of Surgery, Swedish University of Agricultural Sciences, S-750 07 Uppsala, Sweden

Abstract

Progressive retinal atrophy (PRA), a hereditary eye disease leading to blindness, was found in the Abyssinian breed of cat. Sixty-eight cases of a bilateral generalized retinopathy, at different stages of the disease process, were seen in the breed during ophthalmoscopic examinations of cats throughout Sweden during a 2-year period. Forty-five percent of cats aged 2 years or older were affected in the examined group. The earliest case was diagnosed in a 16-month-old cat. At the age of 3–4 years a bilateral retinal atrophy was usually present in affected cats. Genetic analysis indicates that PRA in the Abyssinian cat is caused by an autosomal recessive gene.


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