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The Journal of Heredity 1983:74(4):280-282
© 1983 The American Genetic Association 74:280-282

research-article

Male urinary protein-1 (Mup-1) expression in the female rat

yasushi Kondo, and Junzo Yamada

the Institute of Laboratory Animals, Faculty of Medicine, Kyoto University, yoshida Konoe-cho, Sakyo-ku, Kyoto 606, Japan

Please address reprint request to Dr. Yamada

Abstract

The male urinary protein-1 (Mup-1) gene was detected In female rats on an acrylamide gel electrophorogram by concentrating the urine 100–150 times. The expresslon of Mup-1 in females showed polymorphisms that were confirmed to be controlled by the same alleles observed at the male Mup-1 locus. Moreover, the linkage between Mup-1 and b in females closely coincided with the value found in males. The combined estimate of the recombinatlon frequency was calculated as 8.6 ± 2.9 (9/105). UsIng anti-male MUP-1A serum, the Mup-1 gene was clearly detected on agarose gel electrophorograms of not only intact male but also Intact female urine.


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