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The Journal of Heredity 1984:75(6):498-498
© 1984 The American Genetic Association 75:498

other

Situs inversus in homozygous mice without immotile cilia

Mary Ann Handel, and John R. Kennedy

Department of Zoology and Graduate Program in Cellular, Molecular, and Developmental Biology, University of Tennessee Knoxville, TN 37996

Abstract

Mice homozygous for the mutation situs inversus, lv, are characterized by situs inversus in 50 percent of the individuals. We have investigated the ultrastructure and motility of tracheal cilia and sperm tails in homozygous individuals with and without situs inversus. We found no abnormalities of ciliary structure. Therefore, ciliary immotility is not an essential correlate of situs inversus.


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