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The Journal of Heredity 1985:76(2):107-114
© 1985 The American Genetic Association 76:107-114

research-article

Genes that affect the shape of the murine mandible

Congenic strain analysis

Donald W. Bailey

The author is a senior staff scientist at the Jackson Laboratory, Bar Harbor, ME 04609. He gratefully acknowledges the excellent technical assistance of Evelyn Sargent and Jeannette Reed. This work was supported by NIH Research Grant HD15516 from the National Institute of Child Health and Human Development. The Jackson Laboratory is fully accredited by the American Association for Accreditation of Laboratory Animal Care.

Abstract

Small specific regions of the adult murine mandible are found to be expanded or contracted by the effects of genes sorted out as passenger genes in a set of congenic strains. The large estimated number of such genes could provide a genetic basis for morphological change during speciation.


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