Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Turkula, T. E.
Right arrow Articles by Jalal, S. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Turkula, T. E.
Right arrow Articles by Jalal, S. M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

The Journal of Heredity 1985:76(3):213-214
© 1985 The American Genetic Association 76:213-214

other

Increased rates of sister chromatid exchanges induced by the herbicide 2,4-D

T. E. Turkula, and S. M. Jalal

The authors are, respectively, graduate student and professor of biology at the University of North Dakota, Grand Forks, ND 58202. This study was supported in part by the NSF grant (PRM 81-20271) to S. M. Jalal.

Abstract

The potential for genetic damage from widely used hormonic herbicides, such as 2, 4-dichlorophenoxyacetic acid (2, 4-D), continues to be of serious concern. The mutagenic effect as reflected by the rates of sister chromatid exchanges (SCE) was determined in cultured human lymphocytes. Data were based on the analysis of 50 cells for the control and each of the three treatments. A 50 µg/ml dosage caused a highly significant increase in SCE. Dosages of 100 and 250 µg/ml elevated the rate of SCE, but not significantly. Since 2, 4-D blodegrades rapidly in soil and water, its continued use is not in serious question until safer compounds are available. However, the results of this study suggest that the danger of genetic damage from direct exposure to commercial samples of 2, 4-D should not be ignored.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.