Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Sánchez, E. R.
Right arrow Articles by Erickson, R. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sánchez, E. R.
Right arrow Articles by Erickson, R. P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

The Journal of Heredity 1986:77(5):290-294
© 1986 The American Genetic Association 77:290-294

research-article

Wild-derived Robertsonian translocation in mice: Chromosome 17, Rb (16:17)7, shows novel interactions with t-alleles

Edwin R. Sánchez, and Robert P. Erickson

Edwin Sánchez is currently a post-doctoral fellow with the Department of Pharmacology at the University of Michigan; he was formerly a graduate student in the laboratory of Professor Robert P. Erickson in the Department of Human Genetics, University of Michigan School of Medicine, Ann Arbor, Michigan, 48109. This research was supported by NIH grant HD 11738.

Abstract

We have studied the effects of wild-derived (Rb7) and laboratory-derived (Rb1) Robertsonian translocations involving chromosome 17 on t-complex determined transmission ratio distortion and crossing-over suppression in mice. The Rb7 chromosome is significantly unlike all other wild-type chromosome 17s tested, while Rb1 is not. t0/Rb7 males are uniformly extremely high distorters (>96 percent) while th2/Rb7 males are uniformly extremely low distorters. t0/Rb7 animals allow genetic recombination in the centromere to t-lethal region interval. These observations could be explained if the Rb7 chromosome contains one or more t-like regions.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 GeneticsHome page
F. Pardo-Manuel de Villena and C. Sapienza
Female Meiosis Drives Karyotypic Evolution in Mammals
Genetics, November 1, 2001; 159(3): 1179 - 1189.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.