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The Journal of Heredity 1996:87(1):10-14
© 1996 The American Genetic Association 87:10-14

research-article

Genetic and Physical Mapping of the Chicken IGF1 Gene to Chromosome 1 and Conservation of Synteny With Other Vertebrate Genomes

S. Klein, D. A. Morrice, H. Sang, L. B. Crittenden, and D. W. Burt

From the Federal Research Centre for Agriculture, In stitute for Small Animal Research, Merbitz, lm lnstitut, Nauendorf/Saalkreis Germany
Department of Microbiology, Michigan State University East Lansing, Michigan
Roslin Institute Edinburgh Roslin Midlothian EH25 9PS, U.K.

Address correspondence to Dr. Burt at the ad dress above

Corresponding Editor: J. James Bitgood

Abstract

The chicken insulin-like growth factor has been assigned to the arm of chromosome 1 near the centromere by fluorescence in situ hybidization and genetic linkage analysis. Comparison of physical and fenetic linkage maps loccates the centromere between the I and GAPD loci. Comparison of the genetic maps of chicken and the other vertebrates reveals a highly conserved syntenic group, in cludind the GAPD-LGF1 loci.


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