Skip Navigation

This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (15)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Mariani, P.
Right arrow Articles by Andersson, L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mariani, P.
Right arrow Articles by Andersson, L.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

The Journal of Heredity 1996:87(4):272-276
© 1996 The American Genetic Association 87:272-276

research-article

The Extension Coat Color Locus and the Loci for Blood Group O and Tyrosine Aminotransferase Are on Pig Chromosome 6

P. Mariani, M. Johansson Moller, B. Høyheim, L. Marklund, W. Davies, H. Ellegren, and L. Andersson

Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences Box 597, S-751 24 Uppsala, Sweden
Department of Biochemistry, Physiology, and Nutrition, Norwegian College of Veterinary Medicine Oslo, Norway

Corresponding Editor: James Womack

Abstract

A linkage map of pig chromosome 6 was constructed using a wild pig/Large White intercross pedigree. The map comprises 23 polymorphic loci, and the sex-average map length is {small tilde}170 cM. The study adds three new genes to the chromosome 6 map: the extension (E) coat color locus, and the blood group O (EAO) and tyrosine aminotransferase (TAT) loci. Segregation at the E locus determined two coat color phenotypes among the F2 animals: wild-type color (E/–) and black-spotting (Ep/Ep). The E locus showed close genetic linkage to the most distal marker (S0035) on the short arm of chromosome 6. Comparative coat color genetics as well as comparative mapping strongly suggest that E In pigs encodes the melanocyte-stimulating hormone receptor, as previously shown for the corresponding coat color loci in mouse and cattle. TAT was also mapped to the distal part of 6p, whereas EAO was the most distal marker on 6q. A clear tendency for a higher recombination rate in both terminal regions was observed. A model for the evolution of pig chromosome 6, based on comparative mapping data, is presented.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J HeredHome page
A. Wada, T. Kunieda, M. Nishimura, Y. Kakizoe-Ishida, N. Watanabe, K. Ohkawa, and M. Tsudzuki
A Nucleotide Substitution Responsible for the Tawny Coat Color Mutation Carried by the MSKR Inbred Strain of Mice
J. Hered., March 1, 2005; 96(2): 145 - 149.
[Abstract] [Full Text] [PDF]

Home page
 J ANIM SCIHome page
S. Sato, Y. Oyamada, K. Atsuji, T. Nade, S.-i. Sato, E. Kobayashi, T. Mitsuhashi, K. Nirasawa, A. Komatsuda, Y. Saito, et al.
Quantitative trait loci analysis for growth and carcass traits in a Meishan x Duroc F2 resource population
J Anim Sci, December 1, 2003; 81(12): 2938 - 2949.
[Abstract] [Full Text] [PDF]

Home page
 J HeredHome page
H. Hirooka, D. J. de Koning, J. A. M. van Arendonk, B. Harlizius, P. N. de Groot, and H. Bovenhuis
Genome Scan Reveals New Coat Color Loci in Exotic Pig Cross
J. Hered., January 1, 2002; 93(1): 1 - 8.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
G. Pielberg, C. Olsson, A.-C. Syvanen, and L. Andersson
Unexpectedly High Allelic Diversity at the KIT Locus Causing Dominant White Color in the Domestic Pig
Genetics, January 1, 2002; 160(1): 305 - 311.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
J. M. H. Kijas, M. Moller, G. Plastow, and L. Andersson
A Frameshift Mutation in MC1R and a High Frequency of Somatic Reversions Cause Black Spotting in Pigs
Genetics, June 1, 2001; 158(2): 779 - 785.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
J. M. H. Kijas, R. Wales, A. Törnsten, P. Chardon, M. Moller, and L. Andersson
Melanocortin Receptor 1 (MC1R) Mutations and Coat Color in Pigs
Genetics, November 1, 1998; 150(3): 1177 - 1185.
[Abstract] [Full Text]

Home page
 Genome ResHome page
S. Marklund, J. Kijas, H. Rodriguez-Martinez, L. Rönnstrand, K. Funa, M. Moller, D. Lange, I. Edfors-Lilja, and L. Andersson
Molecular Basis for the Dominant White Phenotype in the Domestic Pig
Genome Res., August 1, 1998; 8(8): 826 - 833.
[Abstract] [Full Text]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.