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Journal of Heredity 2003:94(1)
© 2003 The American Genetic Association 94:107-110

FISH Mapping of Two Putative Keratin Gene Clusters on Cat (Felis catus) Chromosomes

I. Szczerbal, M. Switonski, E. Michalak, N. Rogalska-Niznik, J. Szamalek, and C. Schelling

From the Department of Genetics and Animal Breeding, August Cieszkowski Agricultural University, PoznÄn, Poland (Szczerbal, Switonski, Michalak, Rogalska-Niznik, and Szamalek) and the Department of Animal Sciences, Swiss Federal Institute of Technology and Faculty of Veterinary Medicine, University of Zurich, Zurich, Switzerland (Schelling).

Address correspondence to Marek Switonski, Department of Genetics and Animal Breeding, August Cieszkowski Agricultural University of PoznÄn, Wolynska 33, 60-637 PoznÄn, Poland, or e-mail: switonsk{at}jay.au.poznan.pl.

Genes encoding keratins are evolutionary highly conserved and clustered in two linkage groups in mammalian genomes. Canine keratin 9 (K-9) and keratin 2e (K-2) cosmid-derived gene probes were used to localize the acidic and basic-neutral keratin gene clusters to cat chromosomes E1q12 and B4q15, respectively. The status of the physical map of the cat genome is discussed.


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