Skip Navigation


Journal of Heredity Advance Access originally published online on August 9, 2007
Journal of Heredity 2007 98(6):581-586; doi:10.1093/jhered/esm066
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
98/6/581    most recent
esm066v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (9)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Coyle, S. M.
Right arrow Articles by Peichel, C. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Coyle, S. M.
Right arrow Articles by Peichel, C. L.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The American Genetic Association. 2007. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org.

Parallel Evolution of Pitx1 Underlies Pelvic Reduction in Scottish Threespine Stickleback (Gasterosteus aculeatus)

Susan M. Coyle, Felicity A. Huntingford, and Catherine L. Peichel

From the Division of Evolutionary and Environmental Biology, Graham Kerr Building, University of Glasgow, Scotland, G12 8QQ, UK (Coyle and Huntingford); and the Division of Human Biology, 1100 Fairview Avenue North, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024 (Peichel)

Address correspondence to C. L. Peichel at the address above, or e-mail: cpeichel{at}fhcrc.org.

Little is known about the genetic and molecular mechanisms that underlie adaptive phenotypic variation in natural populations or whether similar genetic and molecular mechanisms are utilized when similar adaptive phenotypes arise in independent populations. The threespine stickleback (Gasterosteus aculeatus) is a good model system to investigate these questions because these fish display a large amount of adaptive phenotypic variation, and similar adaptive phenotypes have arisen in multiple, independent stickleback populations. A particularly striking pattern of parallel evolution in sticklebacks is reduction of skeletal armor, which has occurred in numerous freshwater locations around the world. New genetic and genomic tools for the threespine stickleback have made it possible to identify genes that underlie loss of different elements of the skeletal armor. Previous work has shown that regulatory mutations at the Pitx1 locus are likely responsible for loss of the pelvic structures in independent stickleback populations from North America and Iceland. Here we show that the Pitx1 locus is also likely to underlie pelvic reduction in a Scottish population of threespine stickleback, which has apparently evolved pelvic reduction under a different selection regime than the North American populations.

Corresponding Editor: William Modi

Received September 1, 2006
Accepted May 30, 2007


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 ScienceHome page
Y. F. Chan, M. E. Marks, F. C. Jones, G. Villarreal Jr., M. D. Shapiro, S. D. Brady, A. M. Southwick, D. M. Absher, J. Grimwood, J. Schmutz, et al.
Adaptive Evolution of Pelvic Reduction in Sticklebacks by Recurrent Deletion of a Pitx1 Enhancer
Science, January 15, 2010; 327(5963): 302 - 305.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
C. C. Steiner, H. Rompler, L. M. Boettger, T. Schoneberg, and H. E. Hoekstra
The Genetic Basis of Phenotypic Convergence in Beach Mice: Similar Pigment Patterns but Different Genes
Mol. Biol. Evol., January 1, 2009; 26(1): 35 - 45.
[Abstract] [Full Text] [PDF]

Home page
 Integr. Comp. Biol.Home page
C. J. Schneider
Exploiting genomic resources in studies of speciation and adaptive radiation of lizards in the genus Anolis
Integr. Comp. Biol., October 1, 2008; 48(4): 520 - 526.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.