Journal of Heredity 2003:94(4)
© 2003 The American Genetic Association 94:360-361
Book Review |
Anatomy of Gene Regulation: A Three-Dimensional Structural Analysis
Department of Molecular Biology and Pharmacology Washington University School of Medicine St. Louis, MO 63110
| The first 10% of the full text of this article appears below. |
Panagiotis A. Tsonis. Cambridge University Press, Cambridge, U.K. 2003. 282 pp. $50.00.
Structural biology has revolutionized the way biological questions are approached and the detail with which cellular phenomena are understood. The DNA double helix, the first structure of a biological molecule, was determined by X-ray crystallography in 1953. Seven years later, our first glimpses of the X-ray structures of both myoglobin and hemoglobin were revealed. Since these monumental strides, the field of structural biology has exploded. In 2002, 3,381 new structures were deposited in