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Journal of Heredity Advance Access originally published online on October 26, 2005
Journal of Heredity 2005 96(6):718-721; doi:10.1093/jhered/esi118
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© The American Genetic Association. 2005. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org.

Computer Note

MolKin v2.0: A Computer Program for Genetic Analysis of Populations Using Molecular Coancestry Information

J. P. Gutiérrez, L. J. Royo, I. Álvarez, and F. Goyache

From the Departamento de Producción Animal, Facultad de Veterinaria, Avda. Puerta de Hierro s/n, E-28040-Madrid, Spain (Gutiérrez); and SERIDA-CENSYRA-Somió, C/ Camino de los Claveles 604, E-33203 Gijón (Asturias), Spain (Royo, Álvarez, and Goyache)

Address correspondence to J.P. Gutiérrez at the address above, or e-mail: gutgar@vet.ucm.es.

The first 150 words of the full text of this article appear below.

Recently different studies have formalized the way in which it is possible to obtain coancestry coefficients from molecular information (Caballero and Toro 2002; Eding and Meuwissen 2001) by applying Malécot's (1948) definition of kinship to marker genes, though referring it to identity-by-state instead of identity-by-descent (Caballero and Toro 2002). The molecular coancestry between two individuals, i and j, is the probability that two randomly sampled alleles from the same locus in two individuals are identical by state. Because of its straightforward relationship with genealogical coancestry, this parameter has been shown to have interesting properties that may be used for conservation purposes (Eding et al. 2002; Toro et al., 2002; 2003). Moreover, molecular coancestry can be used to assess genetic diversity within and between populations (Eding and Meuwissen 2001). Using simulated data, Eding and Meuwissen (2001) showed that molecular . . . [Full Text of this Article]


   Program Functions
 

   Input and Output Files
 

   How to Use MolKin: Short Overview
 

   General Comments
 

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