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Journal of Heredity 2003:94(5)
© 2003 The American Genetic Association 94:429-431

Computer Note

DetSel 1.0: A Computer Program to Detect Markers Responding to Selection

R. Vitalis, K. Dawson, P. Boursot, and K. Belkhir

From the School of Biological Sciences, Royal Holloway, University of London, Egham, Surrey TW20 0EX, U.K. (Vitalis); Rothamsted Research, Plant and Invertebrate Ecology Division, Harpenden, Hertfordshire AL5 2JQ, U.K. (Dawson); and the Laboratoire Génome Populations & Interactions, Université Montpellier 2, C. C. 063, Place Eugène Bataillon, 34095 Montpellier Cedex 5, France (Boursot and Belkhir).

Address correspondence to Renaud Vitalis at the address above, or e-mail: Renaud.Vitalis{at}rhul.ac.uk.

Estimating population parameters from polymorphism frequency data requires neutral genetic markers. Any departure from neutrality may invalidate the inferences drawn from such analyses. We recently discussed the possibility of identifying markers that show deviation from neutral expectations in pairwise comparisons of diverging populations. We are now releasing a user-friendly software package that implements all the necessary steps to identify the signature of selection among molecular markers in a set of polymorphism data. This software can be downloaded free of charge at http://www.univ-montp2.fr/~genetix/detsel/detsel.html.


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